By “favorite fictional character” I don’t mean “favorite character of your favorite fiction”, consider the media itself to be irrelevant.
Just consider the character itself and how it changes throughout whichever segments of its timeline, regardless of how the world moves around it (unless it’s relevant);
the show / book / comic / game / political campaign itself may be absolute trash, but you love some character from that more than any other character from anything at all.
Like Magnifico from Wish, or the driver from Big Rigs: Over the Road Racing.
Mass effect had a good line up of really amazing characters.
Controversial opinion, but I feel that all games after the first one were only held up by the characters and worldbuilding - hell, ME2’s plot IS the characters