Save often and don’t worry about save scumming. There are a lot of gotcha traps, especially in the early game, that are funny when they don’t wreck all your progress by propelling you into a bottomless pit.

The game lets you save just about any time, even in dialog right before you pick something to say. Don’t worry too much about failing dialog choices though. Even a failed roll still gives you interesting story. Some interactions might only happen if you failed your roll.

But again, save often because the game can have bugs and can crash or mechanics can work differently than you expect.

There are almost no quests that have a time limit where they count how many long rests you’ve taken. Most of them the game will give you an indication that time is running out, but even if you ignore it the story still makes sense - you’re just too late to finish a quest a certain way.

Almost all quests don’t actually care about time so you can long rest whenever you like and in fact you should rest more often than most gamers probably do because a lot of the story events happen when you sleep.

Often the best tactic in combat is to run away, especially on higher difficulty settings.

P.S. If you’re playing with a controller (e.g. on console) there’s a puzzle in act two that is broken. If you get stuck on a puzzle with colorful lines and brains, it’s not because you’re dumb but because you have to click the left thumb stick to enter precision mode to click things like a computer mouse. Otherwise the things you need to click to solve the puzzle are too far away from the character and you can’t complete it