My main gear currently are an Ifi Zen DAC and some nice Hifiman 4xx plugged into them.
No matter what, I keep coming back to these two. I have other gear, not this is the one that pleases me the most. It is not my endgoal, but it’s superb to my ears.
Topping e50 single end -> Fosi tube amp -> Magnius / Topping e50 balanced -> Magnius. Edifier MR4 and headphones run off the balanced outputs on the Magnius. One button switches between SE and balanced input and the Fosi has bass and treble controls.