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Cake day: August 4th, 2023

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  • You need at least two copies in two different places - places that will not burn down/explode/flood/collapse/be locked down by the police at the same time.

    An enterprise is going to be commissioning new computers or reformatting existing ones at least once per day. This means the bitlocker key list would need printouts at least every day in two places.

    Given the above, it’s easy to see that this process will fail from time to time, in ways like accicentally leaking a document with all these keys.








  • That was one of the original proposed mechanisms to explain how the (obviously false) autism was caused.

    But since then, since thiomersal was removed, other ‘causes’ and moral issues have been invented, including cells from abortions.

    The one that makes me laugh the most is that it’s terrible that the poor poor baby is exposed to so many illnesses (measles, mumps, rubella, polio, tetanus, notovirus, rotovirus and more) in such a short space of time, it’s no wonder the poor dear’s immune system is compromised. And then the same mother drops the kid off at daycare and exposes the poor dear to all those viruses and more - and live viruses at that.

    There is no bleeding logic, just feels. And they get so angry at the fake harm that medicine is causing, and simultaneously actually causing real harms to real people.






  • Sorry for taking a long time to reply.

    with plain old binary fission cell division, how do you get both to divide at the same time, and give each cell one of the new organelles?

    An excellent question! Luckily it was answered in the paper. The researchers actually had a high resolution soft x-ray movie of cell division (ok, an exaggeration, they had a few micrographs showing the sequence). In the sequence, it showed how the organelles (including the novel N2 fixation one) undergoing division and each ‘child’ organelle ending up in different halves.

    Cell division is controlled in the cell by an amazing process:

    • 2 centres are created on opposite sides of the cell
    • Structures like tethers are built that connect each centre to each of the organelles (the nucleus, mitochondria and the N2 fixators). These are called microtubules
    • The microtubules then start shortening, pulling the organelles in two directions, separating them.

    The x-ray micrographs show that the N2 fixators are already integrated into this mitosis mechanism - my guess is that the N2 fixators already ‘understand’ the parent cell’s mitosis signaling.

    The authors also say that the organelles have lost a number of genes for essential cellular functions, relying on the parent cell to provide those capabilities. By comparison, mitochondria have only 37 genes left, and chloroplasts weren’t known for having any DNA when I was at school, but are now known to have about 110 genes.

    In other words, a lot of evolution has already occurred and they are well on the way to being ‘proper’ organelles.




  • As I was discussing this with my partner we summarised this as:

    Humans have always had the capacity for violence and murder; as populations grew, acts of violence could be larger, both in terms of number of combatants and also length of time of continuous fighting. This is a progression of:

    • Small bands of people skirmishing with neighbours to
    • Towns sending small raiding bands to
    • Cities fielding an army for a summer campaign to
    • Empires furnishing professional armies and sending them on multi-year campaigns, to
    • Nation states using advanced logistics to maintain millions of soldiers in the field for years at a time.

    Somewhere between city-states and full modern nation states, there have been full on campaigns of genocide. But genocide can be thought here definitionally as only possible with some significant number of people.

    Unfortunately there is a deep dark part of the human psyche that has always been with us.