I joined Lemmy back in 2020 and have been using it as qaz@lemmy.ml until somewhere in 2023 when I switched to lemmy.world. I’m interested in Linux, FOSS, and several other subjects.

  • 20 Posts
  • 262 Comments
Joined 1 year ago
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Cake day: June 10th, 2023

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  • qaz@lemmy.worldtoProton @lemmy.worldProton Wallet
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    8 days ago

    I don’t see the point to this. All their other products seem to be targeted at replacing less private, non-E2EE services. Mail, calendar, VPN, and a password manager are excellent choices with no major well integrated E2EE solution. This, not so much.

    Also, I don’t really get why they chose Bitcoin, it’s PoW and is much less energy efficient than other alternatives while also not being as private as Monero, nor having things like smart contracts.




  • biochemical effect, placebo = 0

    I’m not sure if the biochemical effects of a placebo are 0.

    In conditioning, a neutral stimulus saccharin is paired in a drink with an agent that produces an unconditioned response. For example, that agent might be cyclophosphamide, which causes immunosuppression. After learning this pairing, the taste of saccharin by itself is able to cause immunosuppression, as a new conditioned response via neural top-down control. Such conditioning has been found to affect a diverse variety of not just basic physiological processes in the immune system but ones such as serum iron levels, oxidative DNA damage levels, and insulin secretion. Recent reviews have argued that the placebo effect is due to top-down control by the brain for immunity and pain. Pacheco-López and colleagues have raised the possibility of “neocortical-sympathetic-immune axis providing neuroanatomical substrates that might explain the link between placebo/conditioned and placebo/expectation responses”. There has also been research aiming to understand underlying neurobiological mechanisms of action in pain relief, immunosuppression, Parkinson’s disease and depression.

    Shamelessly stolen from Wikipedia because I couldn’t find the original source







  • It works super well, and most patients taking it in double blind trials find it relieves headache pain considerably. Why is it a bad thing, to the point of rejecting it as a treatment, that the patient feels that the pill is working very well and has concluded on their own that this is probably not a placebo?

    The problem is that it’s not a double blind trial because the participants can tell whether they are on it. The placebo effect is also a problem because there is no real control group.


  • Lemmy.world has kept open signups open during every large Reddit exodus while many others didn’t. It’s also decently reliable, has decent moderation and is well known. The reason why people didn’t move after is probably because instance migration on Lemmy isn’t possible* so they just stick with what they use.

    *Yes I don’t consider exporting/importing followed communities a migration