A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday.
The U.S. Food and Drug Administration approved Eli Lilly’s drug, named Zepbound. The drug, also known as tirzepatide, helped dieters lose as much as 40 to 60 pounds in testing.
The track record for weight loss drugs is not good. Even “approved” ones. We had a lot of teenagers on amphetamines to make them lose weight.
The podcast Maintenance Phase has at least one episode on them and their history.
The results for this and Wegovy are pretty promising. That said, the long term effects are unknown since they are so new. But the long term effects of having a BMI over 30 are pretty terrible and well known. These are nothing like amphetamines.
The results are that they were only tested on perfectly healthy people which is not indicative of their success in the general population, and the results were also that most people gained the weight back immediately upon stopping the drug.
The side effects were not too bad for people getting the drug for free, but at 1k a month, those side effects cause much higher drop out rates as well.
Still way more promising than anything else available, but not that promising overall.
Eh these people are either gonna be taking bp/cholesterol/diabetes medication or this. Seems like it has the potential to be a wash?
I’m personally a big fan of consuming fewer calories.
Great point, how do you think weight loss drugs work?
They make you less hungry or curb your cravings… Making you eat less.
Not all of them. Some of these drugs can affect nutrient uptake, others are amphetamines to make your resting energy use rise, as a stimulant. I’m sure there are other mechanisms to mess with as well.
Amphetamines basically make you not hungry. That is the primary mechanism anyway.
Or you can just eat less
That’s like telling depressed people “just don’t be so down”. It shows a lack of empathy as well as medical ignorance.
No it isn’t. You can’t choose to not be depressed but you can choose to eat less and accomplish it through willpower.
Where does willpower come from?
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