I know, I know, it can be caused by various factors, like high ISO, poor lighting conditions, long exposure time, heat. (not that I know why the last two cause noise)
But where does noise REALLY come from? What is noise? What does it have to do with photons and photosites?
This guy has got a good grasp and information on digital rendering of images through a camera. ISOless photography and other information is available on the website:
https://clarkvision.com/articles/iso/