• AutoTL;DR@lemmings.worldBEnglish
    3·
    11 months ago

    This is the best summary I could come up with:

    Stan says she tried different therapies but nothing really helped until she found magic mushrooms — which are illegal to produce, possess and sell in Canada without special permission.

    Stan’s experience with microdosing psilocybin is a powerful anecdotal story, but what does the science say about the practice as a potential mental health treatment?

    Once a week they either get a microdose of psilocybin or a placebo, and then Petranker and his team put them through a series of tests to determine if they experience an improvement in their mood.

    Zeina Beidas, the lead research assistant, says microdosing is so trendy right now that many people in the general public simply believe it works.

    Anecdotally, I see young people in particular coming in after using powerful hallucinogenic drugs like psilocybin, and leading to really, really negative mental health outcomes, like even a psychotic episode."

    Andrina Stan, who graduated with a degree in psychology from the University of Toronto, continues to use psilocybin, but she urges others thinking of microdosing to do it safely.

    The original article contains 1,403 words, the summary contains 173 words. Saved 88%. I’m a bot and I’m open source!

    • dimeslime@lemmy.ca
      31·
      11 months ago

      Have you got more details on that? I wouldn’t classify it as a hard reset but I never did the crazy high doses.

      • cheese_greater@lemmy.world
        2·
        11 months ago

        I’m speaking more personally/anecdotally but it can really shift things around from a high 2nd plateau - 4th on. I haven’t done a 4th plateau cuz it scares the fuck out of me but there you have it

        Edit: there seems to be a lot of work being done(+ its very in vogue right now/fashionable) to use ketamine to treat depression. Ketamine is also an anaesthetic and NMDA-antagonist at supra-therapeutic doses…

  • the_q@lemmy.world
    46·
    11 months ago

    I would imagine any belief of efficacy is placebo. Now a heroic dose, that’s where the real change can happen.

    • LostWon@lemmy.ca
      2·
      11 months ago

      Dr. Andrew Huberman’s podcast reviews the available literature here (in the section marked Psychedelics, after 1:34 or go to 1:37 for discussion of a specific study that’s also linked on the page): https://www.hubermanlab.com/episode/understanding-and-conquering-depression

      From what I’ve heard recent years, you don’t get to just (micro)dose up and see what happens. Guidance is needed for there to be actual healing potential. Those of us who have no such trained or even sympathetic person around to help would be taking a big risk. Even having an untrained friend around, you’d just be taking a holiday from your depression and not really treating it.