I turn True Tone off. Everything else I leave as is (brightness about 60%). If you’re going to be printing a lot, you’ll want to calibrate. But if almost or all of your work is digital, the truth is most people will be using a phone to view your work. Androids are all over the maps with their color (previous android owner for years), but iPhones are relatively the same. And the iPhone is extremely close to a MacBook. The last two years, I’ve been making sure it looks good on the MacBook, and because of that it looks great on the majority of people’s phones.
I switched from Nikon to Canon a couple years ago. Bought RF lenses, where before I had regular 1.8 prime lenses. I splurged, and one of the lenses I bought is the 85mm 1.2 which is hands down one of the sharpest lenses I’ve ever seen, and at 1.2 gives a sort of medium format look to portraits. I’ll have this as long as I’m on the RF system.