A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday.

The U.S. Food and Drug Administration approved Eli Lilly’s drug, named Zepbound. The drug, also known as tirzepatide, helped dieters lose as much as 40 to 60 pounds in testing.

  • flicker@kbin.social
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    1 year ago

    I’m on Wegovy and it’s a miracle, frankly.

    Between the ADHD medication wreaking havoc with my hunger signals and the non-diabetic hypoglycemia causing me to go from “not hungry” to “dying of a sugar crash,” the Wegovy gave me actual satiety for the first time in my life, and evened out the crashes.

    I’m a big fan of more options along these lines, for whoever they might save.

    • SeaJ@lemm.ee
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      1 year ago

      Unfortunately people gain the weight back once they stop taking the drug if there is no lifestyle change which there often is not. A guy I know owned a good chunk of Sequence which essentially fast tracked access to Wegovy through telehealth and working with insurance companies. He was pushing to partner with a company that could provide that lifestyle change info so that people could keep off the weight when they stop using it. Weight Watchers bought them so hopefully they can help provide that lifestyle change.

      So far the side effects of Wegovy are fairly standard but it has only been around for 10 years and widely studied for an even shorter period since it has only been on the market for a couple years.

      • flicker@kbin.social
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        1 year ago

        I know that it’s a lifelong drug. I don’t care. I’ll take it. Especially because of the evened out crashes! Not having a sugar high or a sugar low is so wonderful for someone who has spent 37 years enslaved to snacks.

    • Revonult@lemmy.world
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      1 year ago

      Okay so everyone is different but I just found out my non-diabetic hypoglycemia was almost entirly caused by my stimulant ADHD medication. I had been taking it for 12+ years and always thought the hypoglycemia was just how my body was, but it has been night and day. It was very hard to move away the the meds but but I know EXACTLY what you mean by the sudden “dying of sugar crash”. Obviously the ADHD still needs treat but I will be moving to a non-stimulant for treatment.

      • flicker@kbin.social
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        1 year ago

        I’m upvoting you and I’m going to share your story with others but unfortunately I know this isn’t the case with me, as I was adult diagnosis ADHD and dealt with the hypoglycemia since elementary school. I only tried stimulant medication for the first time two years ago.

        But I wonder if any studies have been done about frequency of ADHD and hypoglycemia comorbidities! Seems promising!

  • reluctantpornaccount@reddthat.com
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    1 year ago

    The track record for weight loss drugs is not good. Even “approved” ones. We had a lot of teenagers on amphetamines to make them lose weight.

    The podcast Maintenance Phase has at least one episode on them and their history.

    • SeaJ@lemm.ee
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      1 year ago

      The results for this and Wegovy are pretty promising. That said, the long term effects are unknown since they are so new. But the long term effects of having a BMI over 30 are pretty terrible and well known. These are nothing like amphetamines.

      • ChexMax@lemmy.world
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        1 year ago

        The results are that they were only tested on perfectly healthy people which is not indicative of their success in the general population, and the results were also that most people gained the weight back immediately upon stopping the drug.

        The side effects were not too bad for people getting the drug for free, but at 1k a month, those side effects cause much higher drop out rates as well.

        Still way more promising than anything else available, but not that promising overall.

    • books@lemmy.world
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      1 year ago

      Eh these people are either gonna be taking bp/cholesterol/diabetes medication or this. Seems like it has the potential to be a wash?